AI helps find hidden human proteins and reveals what they do
New research shows how artificial intelligence, combined with advanced experimental science, can help find "hidden" and unexplored proteins in the human body and reveal what they actually do, according to a new study published in Nature.
New research shows how artificial intelligence, combined with advanced experimental science, can help find "hidden" and unexplored proteins in the human body and reveal what they actually do, according to a new study published in Nature.
The short version
- This article has been reviewed according to Science X's editorial process and policies .
- The discovery suggests a new way to study how cells communicate, survive stress and possibly contribute to disease.
- Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, used AI to compare the shapes of more than 214 million predicted proteins.
What happened
Instead of looking only at genetic sequences, they searched by three-dimensional form and found hidden members of the G protein-coupled receptor, or GPCR, family, a group that helps cells sense and respond to extracellular signals. "For decades, we have largely explored protein biology using sequence as our guide," said study senior author Daniel G.
Why it matters
Isom, Ph.D., a Sylvester researcher and faculty member in the Molecular and Cellular Pharmacology Department.
Summary by Nerd News Network. Read the full article at Phys.org via the links above and below.